However, frequent and excessive use of magnesium sulfate or antacid remedies such as Milk of Magnesia can eventually trigger a number of medical problems resulting from other minerals such as sodium, potassium, calcium, or iron getting out of balance. This is more prevalent with kidney diseases and may include fatigue, depression, low blood pressure, dizziness, diarrhea, muscular joint problems, dehydration dry skin, and gastrointestinal or cardiovascular disease... Full Text